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Dosing and Administration Guidelines

The Right
Ratio for
You

ZYUS' cannabinoid formulations are developed with the patient in mind, offering consistent, high-quality formulations carefully designed with specific ratios to make dosing convenient and simple. We encourage discussing the full range of therapeutic options with your healthcare practitioner (“HCP”) so they can tailor a personalized management strategy for your condition. Your HCP will have insight into your medical history that will help them assist you in making an informed decision about how to begin your cannabinoid therapy, especially as it relates to dosing.

Dosing recommendations will vary depending on individual response rates and potential side effects. If you have questions about dosing or product selection, speak with your healthcare practitioner or contact ZYUS Patient Care Centre to schedule a call with a pharmacist.

Step 1

Start with a Low Dose

Step 2

Monitor Symptoms

Step 3

Increase Dose (only if needed)

Step 4

Follow-up with your HCP

Use a journal, such as the ‘ZYUS Track My Journey’ patient journal to monitor your journey with cannabinoids and share your progress with your healthcare practitioner.

Step 1

Start with a Low Dose

Step 2

Monitor Symptoms

Step 3

Increase Dose (only if needed)

Step 4

Follow-up with your HCP

Use a journal, such as the ‘ZYUS Track My Journey’ patient journal to monitor your journey with cannabinoids and share your progress with your healthcare practitioner.

Our Formulations

ZYUS’ topical formulations are designed to penetrate through your skin to provide local targeted relief.

Zylem™ Softgel Capsules (“Zylem Softgels”) are intended for oral administration and provide a simple, convenient, and precise method for dosing cannabinoids. If you are new to cannabinoids, Zylem™ oils may be a better starting point than softgels. Zylem™ oils allow you to start with an even lower dose, monitor symptoms and increase slowly, only if needed.

Zylem™ oil formulations are intended for oral administration and provide patients with the option to start with a low dose, monitor symptoms and slowly increase dose only if needed.

Dosing schedule recommendations will vary depending on individual response rates and potential side effects. Cannabinoids can affect each person differently. It is important that you work with your healthcare practitioner (“HCP”) to select a formulation and a dosing schedule that is right for you. It can take 30 minutes to 2 hours after consumption to begin to feel the effects, but up to 4 hours to feel the full effects. Effects can last up to 12 hours, and some residual effects could last up to 24 hours after use. 1

If you have questions about dosing or product selection, speak with your healthcare practitioner or contact ZYUS Patient Care Centre to schedule a call with a pharmacist.

1. Health Canada. Talk About Cannabis: Cannabis in Canada. https://www.canada.ca/en/health-canada/services/drugs-medication/cannabis/resources.html

How to Take Your ZYLEM Oil Formulation

STEP 1
Open ZYLEM oil formulation bottle

  • To open the bottle, push the bottle cap downward and twist it counter-clockwise. The bottle cap will loosen and you may lift to remove.

STEP 2
Insert syringe into bottle

  • Before insertion, ensure the syringe plunger is pushed down completely. Carefully insert the syringe into the bottle by pressing it downwards. Secure the syringe by twisting it counter-clockwise until its tip is fixed into the bottle mouth.

STEP 3
Draw the dose from bottle

  • Once the syringe is fixed firmly into the bottle, carefully invert the set-up so that the bottle faces downward. Slowly pull the plunger to draw the formulation from the bottle and monitor the amount being extracted using the edge of the plunger. Begin with the dose authorized by your healthcare practitioner (HCP) and titrate accordingly. Remember to track your dosing journey to share with your HCP.

STEP 4
Restore bottle in an upright position

  • Once you have drawn your dose, support the syringe and bottle and slowly re-position the set-up so that your bottle is in an upright position.

STEP 5
Remove syringe from bottle

  • Slowly remove the syringe (by the barrel) from the bottle in an upward motion. Do not remove the syringe by the plunger.

STEP 6
Taking dose from syringe

  • Angle the syringe above your mouth and tilt it downward. Slowly press the plunger to release the formulation and drop carefully into your mouth. Dropping it underneath the tongue is not required. You can take your oil with or without food, although we recommend taking it with a small amount food that are rich in healthy fats as it may increase absorption of the oil and could reduce side effects. Avoid taking your oil with citrus food or drinks as it could interfere with its absorption.

How to Clean Your Syringe

Your syringe should be washed prior to first use and can be re-used once it has been thoroughly cleaned. To clean your syringe:

  1. Disassemble it into its components and carefully clean with dish soap (use sparingly) and water.
  2. Use clean warm water to rinse thoroughly and reassemble the syringe.
  3. Draw hot water into your syringe until it reaches the edge of the plunger.
  4. Shake your syringe and tap it for at least 30 seconds. Press down on the plunger to release water.
  5. Repeat steps 3 – 4 three more times.
  6. Leave syringe disassembled to air dry before next use.


    When cleaning your syringe, ensure you use clean water. Do not reuse water.